Case 1 - Opioid-induced central sleep apnea  pp. 3-10

Opioid-induced central sleep apnea

By Kamal Nasser and Sheldon Kapen

Chapter Abstract

This chapter discusses the case of a 42-year-old patient who was admitted for the evaluation of opioid-induced central sleep apnea. It presents the clinical history, examination, follow-up, treatment, and the results of the procedures performed on the patient. The patient was presented for evaluation of frequent breathing pauses during sleep, which had been witnessed by his wife for 5 years along with intermittent mild snoring. His social history was negative for alcohol or other substance abuse, but he was an ex-smoker and he drank 12 cups of coffee per day. The patient had been maintained on narcotics for treatment of his chronic pain following the laminectomy, for a period of 8 years. In view of his sleep respiratory symptoms, polysomnography (PSG) was performed. Opioid-induced central sleep apnea (CSA) has attracted attention in recent years because of the surge in opioid administration to patients with pain.


Keywords:

chronic pain; social history; intermittent mild snoring; polysomnography; respiratory symptoms; central sleep apnea; narcotics; laminectomy;

Case 1

Reference Title: Suggested reading

Reference Type: further-reading

Bradley TD , Logan AG , Kimoff RJ , et al. Continuous positive airway pressure for central sleep apnea and heart failure. N Engl J Med 2005; 353: 2025–33.
Farney RJ , Walker JM , Cloward TV , Rhondeau S. Sleep-disordered breathing associated with long-term opioid therapy. Chest 2003; 123: 632–9.
Guilleminault C , Eldridge FL , Dement WC. Insomnia with sleep apnea: a new syndrome. Science 1973; 181: 856–8.
Mogri M , Khan M , Grant B , Mador, J. Central sleep apnea induced by acute ingestion of opioids. Chest 2008; 133: 1484–8.
Walker JM , Farney RJ , Rhondeau SM , et al. Chronic opioid use is a risk factor for the development of central sleep apnea and ataxic breathing. J Clin Sleep Med 2007; 3: 455–61.
Wang D , Teichtahl H , Drummer O , et al. Central sleep apnea in stable methadone maintenance treatment patients. Chest 2005; 128: 1348–56.
Webster LR , Choi Y , Desaih H , Grant BJ. Sleep-disordered breathing and chronic opioid therapy. Pain Med 2008; 9: 425–32.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Review

Reference Type: further-reading

Eckert DJ , Malhotra A , Jordan AS. Mechanisms of apnea. Prog Cardiovasc Dis 2009; 51: 313–23.

Reference Title: General

Reference Type: further-reading

Badr MS. Central sleep apnea. Prim Care Clin Office Pract 2005; 32: 361–74.
Dauvilliers Y , Stal V , Abril B , et al. Chiari malformation and sleep related breathing disorders. J Neurol Neurosurg Psychiatry 2007; 78: 1344–8.
Murray C , Seton C , Prelog K , Fitzgerald DA. Arnold Chiari type I malformation presenting with sleep disordered breathing in well children. Arch Dis Child 2006; 91: 342–3.
Yglesias A , Narbona J , Vanaclocha V , Artieda J. Chiari type I malformation, glossopharyngeal neuralgia and central sleep apnea in a child. Dev Med Child Neurol 1996; 38: 1126–30.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Bannister R , Gibson W , Michaels L , Oppenheimer DR. Laryngeal abductor paralysis in multiple system atrophy. A report on three necropsied cases, with observations on the laryngeal muscles and the nuclei ambigui. Brain 1981; 104: 351–68.

Reference Title: Review

Reference Type: further-reading

Silber MH , Levine S. Stridor and death in multiple system atrophy. Mov Disord 2000; 158: 699–704.

Reference Title: General

Reference Type: further-reading

Gilman S , Wenning GK , Low PA , et al. Second consensus statement on the diagnosis of multiple system atrophy. Neurology 2008; 71: 670–6.
Holinger LD. Etiology of stridor in the neonate, infant and child. Ann Otol Rhinol Laryngol 1980; 89: 397–400.
Iranzo A , Santamaría J , Tolosa E , et al. Long-term effect of CPAP in the treatment of nocturnal stridor in multiple system atrophy. Neurology 2004; 63: 930–2.
Vetrugno R , Provini F , Cortelli P , et al. Sleep disorders in multiple system atrophy: a correlative video-polysomnographic study. Sleep Med. 2004; 5: 21–30.
Vetrugno R , Liguori R , Cortelli P , et al. Sleep-related stridor due to dystonic vocal cord motion and neurogenic tachypnea/tachycardia in multiple system atrophy. Mov Disord 2007; 22: 673–8.

Reference Title: Suggested reading

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specification. Westchester, Illinois: American Academy of Sleep Medicine, 2007.
AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
American Thoracic Society . Standards and indications for cardiopulmonary sleep studies in children. Am J Respir Crit Care Med 1996; 153: 866–78.
Guilleminault C , Korobkin R , Winkle R. A review of 50 children with obstructive sleep apnea syndrome. Lung 1981; 159: 275–87.
Rosen CL , Anderea LD , Haddad GG. Adult criteria for obstructive sleep apnea do not identify children with serious obstruction. Am Rev Respir Dis 1992; 146: 1231–4.
Ward SL , Marcus CL. Obstructive sleep apnea in infants and young children. J Clin Neurophysiol 1996; 13: 198–207.

Reference Title: Suggested reading

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Hungs M , Mignot E . Hypocretin/orexin, sleep and narcolepsy. Bioessays 2001; 23: 397–408.
Lu J , Sherman D , Devor M , et al. A putative flip–flop switch for control of REM sleep. Nature 2006; 441: 589–94.
Morgenthaler TI , Kapur VK , Brown T , et al. Standards of Practice Committee of the American Academy of Sleep Medicine. Practice parameters for the treatment of narcolepsy and other hypersomnias of central origin. Sleep 2007; 30: 1705–11.
Nevsimalova S . Narcolepsy in childhood. Sleep Med Rev 2009; 13: 169–80.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Passouant P. The history of narcolepsy. In: Guilleminault C , Dement WC , Passouant P , eds. Narcolepsy. New York: Spectrum, 1976; 3–14.
Wilson S. The narcolepsies. Brain 1928; 51: 63–77.

Reference Title: Review

Reference Type: further-reading

Baumann CR , Bassetti CL. Hypocretins (orexins) and sleep-wake disorders. Lancet Neurol 2005; 4: 673–82.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Littner MR , Kushida C , Wise M , et al. Practice parameters for clinical use of the multiple sleep latency test and the maintenance of wakefulness test. Sleep 2005; 28: 113–21.
Mignot E , Lammers GJ , Ripley B , et al. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch Neurol 2002; 59: 1553–62.
Morgenthaler TI , Kapur VK , Brown T , et al. Standards of Practice Committee of the American Academy of Sleep Medicine. Practice parameters for the treatment of narcolepsy and other hypersomnias of central origin. Sleep 2007; 30: 1705–11.
Silber MH , Rye DB. Solving the mystery of narcolepsy. The hypocretin story. Neurology 2001; 56: 1616–18.
Weaver TE , Cuéllar N. A randomized trial evaluating the effectiveness of sodium oxybate therapy on quality of life in narcolepsy. Sleep 2006; 29: 1189–94.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Yoss RE , Daly DD . Criteria for the diagnosis of the narcoleptic syndrome. Mayo Clin Proc 1957; 32: 320–8.

Reference Title: Review

Reference Type: further-reading

Bassetti CL. Narcolepsy. In: Culebras A , ed. Sleep Disorders and Neurological Diseases, 2nd edn. New York: Informa Healthcare, 2007; 83–116.

Reference Title: General

Reference Type: further-reading

Auger RR , Goodman SH , Silber MH , et al. Risks of high dose stimulants in the treatment of disorders of excessive somnolence: a case–control study. Sleep 2005; 28: 667–72.
Douglass AB , Hays P , Pazderka F , Russel JM . Florid refractory schizophrenias that turn out to be treatable variants of HLA-associated narcolepsy. J Nerv Ment Dis 1991; 179: 12–17.
Guilleminault C , Pelayo R . Narcolepsy in prepubertal children. Ann Neurol 1998; 43: 135–42.
Kondziella D , Arlien-Soborg P . Diagnostic and therapeutic challenges in narcolepsy-related psychosis. J Clin Psychiatry 2006; 67: 1817–19.
Krahn LE , Hansen MR , Shepard JW . Pseudocataplexy. Psychosomatics 2001; 42: 356–8.
Parkes JD , Baraitser M , Marsden CD , Asselman P . Natural history, symptoms and treatment of the narcoleptic syndrome. Acta Neurol Scand 1975; 52: 337–53.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Review

Reference Type: further-reading

Wise MS , Arand Dl , Auger RR , Brooks SN , Watson NF. Treatment of narcolepsy and other hypersomnias of central origin. An American Academy of Sleep Medicine Review. Sleep 2007; 30: 1712–27.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, revised: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2001.
AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Anic-Labat S , Guilleminault C , Kraemer HC , et al. Validation of a cataplexy questionnaire in 983 sleep-disorders patients. Sleep 1999; 22: 77–87.
Hayduk RM , Erman M , Mitler MM. Treatment of cataplexy with sodium oxybate: transition from tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs). Sleep 2 (abstract supplement), 2003.
Hublin C , Kaprio J , Partinen M , Koskenvuo M , Heikkila K. The Ullanlinna Narcolepsy Scale: validation of a measure of symptoms in the narcoleptic syndrome. J Sleep Res 1994; 3: 52–9.
Parkes JD , Chen SY , Clift SJ , Dahlitz MJ , Dunn G. The clinical diagnosis of the narcoleptic syndrome. J Sleep Res 1998; 7: 41–52.
Thorpy M. Therapeutic advances in narcolepsy. Sleep Med 2007; 8: 427–40.
Vignatelli L , D'Alessandro R , Candelise L. Antidepresant drugs for narcolepsy. Cochrane Database of Systematic Reviews 2008, Issue 1. Art. No CD003724. DOI: 10.1002/14651858. CD003724. pub3.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Schenck CH , Bundlie SR , Ettinger MG , Mahowald MW. Chronic behavioral disorders of human REM sleep: a new category of parasomnia. Sleep 1986; 9: 293–308.

Reference Title: General

Reference Type: further-reading

Boeve BF , Silber MH , Saper CB , et al. Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease. Brain 2007; 130: 2770–88.
Iranzo A , Santamaría J , Tolosa E. The clinical and pathophysiological relevance of REM sleep behavior disorder in neurodegenerative diseases. Sleep Med Rev 2009; 13: 385–401.
Schenck CH , Bundlie SR , Mahowald MW. Delayed emergence of a parkinsonian disorder in 38% of 29 older men initially diagnosed with idiopathic rapid eye movement sleep behavior disorder. Neurology 1996; 46: 388–93.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Bokey K. Conversion disorder revisited: severe parasomnia discovered. Aust N Z J Psychiatry 1993; 27: 694.

Reference Title: Review

Reference Type: further-reading

Schenck CH , Mahowald MW. Rapid eye movement sleep parasomnias. Neurol Clin 2005; 23: 1107–26.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Kushida CA , Clerk AA , Kirsch CM , et al. Prolonged confusion with nocturnal wandering arising from NREM and REM sleep: a case report. Sleep 1995; 18: 757–64.
Lombardi C , Vetrugni R , Provini F , et al. Harlequin syndrome: an association with overlap parasomnia. J Neurol Neurosurg Psychiatry 2004; 75: 341–2.
Mahowald MW , Schenck CH. Dissociated states of wakefulness and sleep. Neurology 1992; 42: 44–52.
Schenck CH , Boyd JL , Mahowald MW. A parasomnia overlap disorder involving sleepwalking, sleep terrors, and REM sleep behavior disorder in 33 polysomnographically confirmed cases. Sleep 1997; 20: 972–81.
Young P. Genetic aspects of parasomnias. Somnologie 2008; 12: 7–13.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Mitchell SW. On some of the disorders of sleep. Virginia Med Monthly 1876; 2: 769–81.

Reference Title: Review

Reference Type: further-reading

Sandyk R. Resolution of sleep paralysis by weak electromagnetic fields in a patient with multiple sclerosis. Int J Neurosci 1997; 90: 145–57.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Awadalla A , Al-Fayez G , Harville M , et al. Comparative prevalence of isolated sleep paralysis in Kuwaiti, Sudanese, and American college students. Psychol Rep 2004; 95: 317–22.
Cheyne JA. Sleep paralysis episode frequency and number, types, and structure of associated hallucinations. J Sleep Res 2005; 14: 319–24.
de Jong JT. Cultural variation in the clinical presentation of sleep paralysis. Transcult Psychiatry 2005; 42: 78–92.
Girard TA , Cheyne JA. Timing of spontaneous sleep-paralysis episodes. J Sleep Res 2006; 15: 222–9.
Mitler MM , Hajdukovic R , Erman M , Koziol JA. Narcolepsy. J Clin Neurophysiol 1990; 7: 93–118.
Ohaeri JU , Awadalla A , Makanjuola VA , Ohaeri BM. Features of isolated sleep paralysis among Nigerians. East Afr Med J 2004; 81: 509–19.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Bokey K. Conversion disorder revisited: severe parasomnia discovered. Aust N Z J Psychiatry 1993; 27: 694.
Schenck CH , Boyd JL , Mahowald MW. A parasomnia overlap disorder involving sleepwalking, sleep terrors, and REM sleep behavior disorder in 33 polysomnographically confirmed cases. Sleep 1997; 20: 972–81.

Reference Title: Review

Reference Type: further-reading

Mahowald MW , Schenck CH. Dissociated states of wakefulness and sleep. Neurology 1992; 42: 44–52.

Reference Title: General

Reference Type: further-reading

American Academy of Sleep Medicine . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Lombardi C , Vetrugn OR , Provini F , et al. Harlequin syndrome: an association with overlap parasomnia. J Neurol Neurosurg Psychiatry 2004; 75: 341–2.
Schenck CH , Mahowald MW. Rapid eye movement sleep parasomnias. Neurol Clin 2005; 23: 1107–26.
Schenkel E , Siegel JM. REM sleep without atonia after lesions of the medial medulla. Neurosci Lett 1989; 98: 159–65.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Geer JH , Silverman I. Treatment of a recurrent nightmare by behavior-modification procedures: a case study. J Abnorm Psychol 1967; 72: 188–90.

Reference Title: Review

Reference Type: further-reading

Lancee J , Spoormaker VI , Krakow B , van den Bout J. A systematic review of cognitive-behavioral treatment for nightmares: toward a well-established treatment. J Clin Sleep Med 2008; 4: 475–80.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Krakow B , Kellner R , Neidhardt J , Pathak D , Lambert L. Imagery rehearsal treatment of chronic nightmares: with a thirty month follow-up. J Behav Ther Exp Psychiatry 1993; 24: 325–30.
Krakow BJ , Kellner R , Pathak D , Lambert L. Imagery rehearsal treatment for chronic nightmares. Behav Res Ther 1995; 33: 837–43.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Schenck CH , Bundlie SR , Mahowald MW. Human REM sleep chronic behavior disorders: a new category of parasomnia. Sleep Res 1985; 14: 208.

Reference Title: Reviews

Reference Type: further-reading

Afifi AK , Bergman RA. Reticular formation, wakefulness, and sleep. In: Afifi AK , Bergman RA , eds. Functional Neuroanatomy, Text and Atlas, 2nd edn. New York: McGraw-Hill, 2005, 398–406.
Dyken ME , Yamada T , Lin-Dyken DC. Polysomnographic assessment of spells in sleep: nocturnal seizures versus parasomnias. Semin Neurol 2001; 21: 377–90.
Mahowald MW , Schenck CH. REM sleep parasomnias. In: Kryger MH , Roth T , Dement WC , eds. Principles and Practice of Sleep Medicine, 4th edn. Philadelphia: Elsevier Saunders, 2005; 897–916.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Culebras A , Moore JT. Magnetic resonance findings in REM sleep behavior disorder. Neurology 1989; 39: 1519–23.
Dyken ME , Im KB. Sleep-disordered breathing and stroke. In: Silber MH , ed. Sleep Medicine Clinics, Vol. 3: Neurologic Disorders and Sleep. Philadelphia: Elsevier Saunders, 2008; 361–76.
Dyken ME , Yamada T. Narcolepsy and disorders of excessive somnolence. Prim Care 2005; 32: 389–413.
Dyken ME , Lin-Dyken DC , Seaba P , et al. Violent sleep-related behavior leading to subdural hemorrhage. Arch Neurol 1995; 52: 318–21.
Dyken ME , Yamada T , Ali Moshin. Treatment of hypersomnias. In: Kushida CA , ed. Handbook of Sleep Disorders, 2nd edn. New York: Informa, 2009; 299–320.
Trenkwalder, C. Parkinsonism. In: Kryger MH , Roth T , Dement WC , eds. Principles and Practice of Sleep Medicine, 4th edn. Philadelphia: Elsevier Saunders, 2005; 801–10.
Xi Z , Luning W. REM sleep behavior disorder in a patient with pontine stroke. Sleep Medicine 2009; 10: 143–6.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Reviews

Reference Type: further-reading

Howell MJ , Schenck CH , Crow SJ. A review of nighttime eating disorders. Sleep Med Rev 2009 13: 23–34.
Schenck CH , Arnulf I , Mahowald MW. Sleep and sex: what can go wrong? A review of the literature on sleep related disorders of abnormal sexual behaviors and experiences. Sleep 2007; 30: 683–702.

Reference Title: General

Reference Type: further-reading

Andersen ML , Poyares D , Alves RSC , Skomo R , Tufik S. Sexsomnia: abnormal sexual behavior during sleep. Brain Res Rev 2007; 56: 271–82.
Dolder CR , Nelson MH. Hypnosedative-induced complex behaviours: incidence, mechanisms, and management. CNS Drugs 2008; 22: 1021–36.
Franco RA , Ashwanthnarayan R , Deshpandee A , et al. The high prevalence of restless legs syndrome in liver disease in an academic-based hepatology practice. J Clin Sleep Med 2008; 4: 45–9.
Wills L , Garcia J . Parasomnias: epidemiology and management. CNS Drugs 2002; 16: 803–10.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Gastaut H , Broughton R. A clinical and polygraphic study of episodic phenomena during sleep. Biol Psychiatry 1965; 7: 197–221.
Jones E. On the Nightmare. London: Hogarth, 1949.

Reference Title: Review

Reference Type: further-reading

Crisp AH. The sleepwalking/night terrors syndrome in adults. Postgrad Med J 1996; 72: 599–604.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Bruni O , Ferri R , Miano S , Verrillo E. L-5-hydroxytryptophan treatment of sleep terrors in children. Eur J Pediatr 2004; 163: 402–7.
Di Gennaro G , Autret A , Mascia A , et al. Night terrors associated with thalamic lesion. Clin Neurophysiol 2004; 115: 2489–92.
Hauri PJ , Silber MH , Boeve BF. The treatment of parasomnias with hypnosis: a 5-year follow-up study. J Clin Sleep Med 2007; 3: 369–73.
Hublin C , Kaprio J. Genetic aspects and genetic epidemiology of parasomnias. Sleep Med Rev 2003; 7: 413–21.
Ohayon MM , Guilleminault C , Priest RG. Night terrors, sleepwalking, and confusional arousals in the general population: their frequency and relationship to other sleep and mental disorders. J Clin Psychiatry 1999; 60: 268–76.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Broughton RJ. Sleep disorders: disorders of arousal? Enuresis, somnambulism, and nightmares occur in confusional states of arousal, not in “dreaming sleep.” Science 1968; 159: 1070–8.

Reference Title: Review

Reference Type: further-reading

Pressman MR. Factors that predispose, prime and precipitate NREM parasomnias in adults: clinical and forensic implications. Sleep Med Rev 2007; 11: 5–30.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Ohayon MM , Guilleminault C , Priest RG. Night terrors, sleepwalking, and confusional arousals in the general population: their frequency and relationship to other sleep and mental disorders. J Clin Psychiatry 1999; 60: 268–76.
Plazzi G , Tinuper P , Montagna P , Provini F , Lugaresi E. Epileptic nocturnal wanderings. Sleep 1995; 18: 749–56.
Sansone RA , Sansone LA. Zolpidem, somnambulism, and nocturnal eating. Gen Hosp Psychiatry 2008; 30: 90–1.
Schenck CH , Pareja JA , Patterson AL , Mahowald MW. Analysis of polysomnographic events surrounding 252 slow-wave sleep arousals in thirty-eight adults with injurious sleepwalking and sleep terrors. J Clin Neurophysiol 1998; 15: 159–66.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Review

Reference Type: further-reading

Joncas S , Zadra A Z , Paquet J , Montplaisir J. The value of sleep deprivation as a diagnostic tool in adult sleepwalkers. Neurology 2002; 58: 936–40.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding ManualM. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Hughes JR. A review of sleepwalking (somnambulism): the enigma of neurophysiology and polysomnography with differential diagnosis of complex partial seizures. Epilepsy Behav 2007; 11: 483–91.
Mayer G , Meissner V , Schwarzmaier P , Meier-Ewert K. Sleep deprivation in somnambulism. Effect of arousal, deep sleep and sleep stage changes. Nervenartz 1998; 69: 495–501.
Pilon M , Montplaisir J , Zadra A. Precipitating factors of somnambulism. Impact of sleep deprivation and forced arousals. Neurology 2008; 70: 2284–90.
Pressman MR. Factors that predispose, prime and precipitate NREM parasomnias in adults: clinical and forensic implications. Sleep Med Rev 2007; 11: 5–30; discussion 31–3.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Stunkard AJ , Grace WF , Wolff HG. The night-eating syndrome: a pattern of food intake among certain obese patients. Am J Med 1955; 19: 78–86.

Reference Title: Review

Reference Type: further-reading

Howell MJ , Schenck CH , Crow SJ. A review of nighttime eating disorders. Sleep Med Rev 2009; 13: 23–34.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Provini F , Albani F , Vetrugno R , et al. A pilot double-blind placebo-controlled trial of low-dose pramipexole in sleep-related eating disorder. Eur J Neurol 2005; 12: 432–6.
Provini F , Antelmi E , Vignatelli L , et al. Association of restless legs syndrome with nocturnal eating: a case–control study. Mov Disord 2009; 24: 871–7.
Schenck CH , Hurwitz TD , Bundlie SR , Mahowald MW. Sleep-related eating disorders: polysomnographic correlates of a heterogeneous syndrome distinct from daytime eating disorders. Sleep 1991; 14: 419–31.
Vetrugno R , Manconi M , Ferini-Strambi L , et al. Nocturnal eating: sleep-related eating disorder or night eating syndrome? A videopolysomnographic study. Sleep 2006; 29: 949–54.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Review

Reference Type: further-reading

Howell MJ , Schenck, CH , Crow, SJ. A review of nighttime eating disorders. Sleep Med 2009; 13: 23–34.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
De Ocampo J , Flodvary N , Dinner DS , Golish J. Sleep-related eating disorder in fraternal twins. Sleep Med 2002; 3: 525–6.
Provini F , Antelmi E , Vignatelli L , et al. Association of restless legs syndrome with nocturnal eating: a case–control study. Mov Disord 2009; 24: 871–7.
Spaggiari MC , Granella F , Parrino L , et al. Nocturnal eating syndrome in adults. Sleep 1994; 17: 339–44.
Striegel-Moore RH , Franko DL , Thompson D , Affenito S , Kraemer HC. Night eating: prevalence and demographic correlates. Obesity (Silver Spring) 2006; 14: 139–47.
Vetrugno R , Manconi M , Ferini-Strambi L , et al. Nocturnal eating: sleep-related eating disorder or night eating syndrome? A videopolysomnographic study. Sleep 2006; 29: 949–54.
Winkelman JW. Treatment of nocturnal eating syndrome and sleep-related eating disorder with topiramate. Sleep Med 2003; 4: 243–6.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Review

Reference Type: further-reading

Howell MJ , Schenck CH , Crow SJ. A review of nighttime eating disorders. Sleep Med Rev 2009; 13: 23–34.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . Sleep related eating disorder. In: International Classification of Sleep Disorder, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Guilleminault C , Zupancic M. Obstructive sleep apnea syndrome. In: S. Chokroverty , ed. Sleep Disorders Medicine: Basic Science, Technical Considerations, and Clinical Aspects, 3rd edn. Saunders Elsevier, 2009; 319–39.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Reviews

Reference Type: further-reading

Manford M , Andermann F. Complex visual hallucinations. Clinical and neurobiological insights. Brain Res 1998; 121: 1819–40.
Silber MH , Hansen MR , Girish M. Complex nocturnal visual hallucinations. Sleep Med 2005; 6: 363–6.

Reference Title: General

Reference Type: further-reading

Fenelon G , Mahieux F , Huon R , Ziegler M. Hallucinations in Parkinson's disease: prevalence, phenomenology and risk factors. Brain 2000; 123: 733–45.
Kavey NB , Whyte J. Somnambulism associated with hallucinations. Psychosomatics 1993; 34: 86–90.
Teunisse R , Cruysberg J , Verbeek A , et al. The Charles Bonnet syndrome: a large prospective study in the Netherlands. A study of the prevalence of the Charles Bonnet syndrome and associated factors in 500 patients attending the University Department of Ophthalmology at Nijmegen. Br J Psychiatry 1995; 166: 254–7.

Reference Title: Suggested reading

Reference Type: further-reading

De Roeck J , Van Hoof E. Sleep-related expiratory groaning: a case report. Sleep Res 1983; 12: 377.
Pevernagie DA , Boon PA , Mariman ANN , Verhaeghen DB , Pauwels RA. Vocalization during episodes of prolonged expiration: a parasomnia related to REM sleep. Sleep Med 2001; 2: 19–30.
Vetrugno R , Provini F , Plazzi G , et al. Catathrenia (nocturnal groaning): a new type of parasomnia. Neurology 2001; 56: 681–3.
Vetrugno R , Lugaresi E , Plazzi G , et al. Catathrenia (nocturnal groaning): an abnormal respiratory pattern during sleep. Eur J Neurol 2007; 14: 1236–43.
Vetrugno R , Lugaresi E , Ferini-Strambi L , Montagna P. Catathrenia (nocturnal groaning): what is it? Sleep 2008; 31: 308–9.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Review

Reference Type: further-reading

Schenck CH , Arnulf I , Mahowald MW. Sleep and sex: what can go wrong? A review of the literature on sleep related disorders and abnormal sexual behaviors and experiences. Sleep 2007; 30: 683–702.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Guilleminault C , Moscovitch A , Yuen K , Poyares D. Atypical sexual behavior during sleep. Psychosom Med 2002; 64: 328–36.
Rosenfeld DS , Elhajjar AJ. Sleepsex: a variant of sleepwalking. Arch Sex Behav 1998; 27: 269–78.
Schenck CH , Mahowald MW. Parasomnias associated with sleep-disordered breathing and its therapy, including sexsomnia as a recently recognized parasomnia. Somnology 2008; 12: 38–49.
Shapiro CM , Trajanovic N , Fedoroff JP. Sexsomnia – a new parasomnia? Can J Psychiatry 2003; 48: 311–17.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Lugaresi E , Cirignotta F. Hypnogenic paroxysmal dystonia; epileptic seizures or a new syndrome? Sleep 1981; 4: 129–38.

Reference Title: Review

Reference Type: further-reading

Tinuper P , Provini F , Bisulli F , et al. Movement disorders in sleep: guidelines for differentiating epileptic from non-epileptic motor phenomena arising from sleep. Sleep Med Rev 2007; 11: 255–67.

Reference Title: General

Reference Type: further-reading

Nobili L , Francione S , Mai R , et al. Surgical treatment of drug-resistant nocturnal frontal lobe epilepsy. Brain 2007; 130: 561–73.
Oldani A , Manconi M , Zucconi M , Martinelli C , Ferini-Strambi L. Topiramate treatment for nocturnal frontal lobe epilepsy. Seizure 2006; 15: 649–52.
Provini F , Plazzi G , Tinuper P , et al. Nocturnal frontal lobe epilepsy. A clinical and polygraphic overview of 100 consecutive cases. Brain 1999; 122: 1017–31.
Scheffer IE , Bhatia KP , Lopes-Cendes I , et al. Autosomal dominant nocturnal frontal lobe epilepsy: a distinctive clinical disorder. Brain 1995; 118: 61–73.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Review

Reference Type: further-reading

Provini F , Plazzi G , Tinuper P , et al. Nocturnal frontal lobe epilepsy. A clinical and polygraphic overview of 100 consecutive cases. Brain 1999; 122: 1017–31.

Reference Title: General

Reference Type: further-reading

Derry CP , Davey M , Johns M , et al. Distinguishing sleep disorders from seizures: diagnosing bumps in the night. Arch Neurol 2006; 63: 705–9.
Shouse MN , Mahowald MW. Epilepsy, sleep and sleep disorders. In: Kryger MH , Roth T , Dement WC , eds. Principles and Practice of Sleep Medicine. Philadelphia: Elsevier Saunders, 2005; 863–78.
Tinuper P , Provini F , Bisulli F , et al. Movement disorders in sleep: guidelines for differentiating epileptic from non-epileptic motor phenomena arising from sleep. Sleep Med Rev 2007; 11: 255–67.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Gastaut H , Broughton R. Epileptic Seizures. Springfield, Illinois: Charles C Thomas; 1972.

Reference Title: Review

Reference Type: further-reading

Dyken ME , Yamada T , Lin-Dyken DC. Polysomnographic assessment of spells in sleep: nocturnal seizures versus parasomnias. Semin Neurol 2001; 21: 377–90.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Klass DW. Electroencehalographic mechanisms of complex partial seizures. In: Penry JK , Daly DD , eds. Complex Partial Seizures and Their Treatment. New York: Raven Press; 1975: 113–40.
Klass DW , Espinosa RE , Fischer-Williams M. Analysis of concurrent electroencephalographic and clinical events occurring sequentially during partial seizures [Abstract]. Electroencephalogr Clin Neurophysiol 1973; 34: 728.

Reference Title: Suggested reading

Reference Type: further-reading

Dyken ME , Yamada T , Lin-Dyken DC. Polysomnographic assessment of spells in sleep: nocturnal seizures versus parasomnias. Semin Neurol 2001; 21: 377–90.
Provini F , Plazzi G , Tinuper P , et al. Nocturnal frontal lobe epilepsy. A clinical and polygraphic overview of 100 consecutive cases. Brain 1999; 122: 1017–31.
Ryvlin P , Rheims S , Risse G. Nocturnal frontal lobe epilepsy. Epilepsia 2006; 47: 83–6.
Tao JX , Ray A , Hawes-Ebersole S , et al. Intracranial EEG substrates of scalp EEG interictal spikes. Epilepsia 2005; 46: 669–76.
Tao JX , Baldwin M , Ray A , et al. The impact of cerebral source area and synchrony on recording scalp electroencephalography ictal patterns. Epilepsia 2007; 48: 2167–76.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Beaussart M. Benign epilepsy of childhood with rolandic (centrotemporal) paroxysmal foci. Epilepsia 1972; 13: 795–811.

Reference Title: Reviews

Reference Type: further-reading

Capovilla G , Striano P , Beccaria F. Changes in Panayiotopoulos syndrome over time. Epilepsia 2009; 50 (Suppl. 5): S45–S8.
Gobbi G , Boni A , Filippini M. The spectrum of idiopathic Rolandic epilepsy syndromes and idiopathic occipital epilepsies: from the benign to the disabling. Epilepsia 2006; 47 (Suppl. 2): S62–S6.
Kramer U. Atypical presentations of benign childhood epilepsy with centrotemporal spikes: a review. J Child Neurol 2008; 23: 785–90.
Nickels K , Wirrell E. Electrical status epilepticus in sleep. Semin Pediatr Neurol 2008; 15: 50–60.

Reference Title: General

Reference Type: further-reading

Son CD , Moss FJ , Cohen BN , Lester HA. Nicotine normalizes intracellular subunit stoichiometry of nicotinic receptors carrying mutations linked to autosomal dominant nocturnal frontal lobe epilepsy. Mol Pharmacol 2009; 75: 1137–48.
Zacconi M , Ferini-Strambi L. NREM parasomnias: arousals and differentiation from nocturnal frontal lobe epilepsy. Clin Neurophysiol 2000; 111 (Suppl. 2): S129–S35.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Tinuper P , Cerullo A , Cirignotta F , et al. Nocturnal paroxysmal dystonia with short lasting attacks: three cases with evidence for an epileptic frontal lobe origin of seizures. Epilepsia 1990; 31: 549–56.

Reference Title: Reviews

Reference Type: further-reading

Mahowald M , Schenck C. Non-rapid eye movement sleep parasomnias. Neurolog Clin 2005; 23: 1077–106.
Zucconi M , Ferini-Strambi L. NREM parasomnias: arousal disorders and differentiation from nocturnal frontal lobe epilepsy. Clin Neurophysiol 2000; 111 (Suppl. 2); S129–S35.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Harris M , Grunstein R. Treatments for somnambulism in adults: assessing the evidence. Sleep Med Rev 2009; 13: 295–7.
Pilon M , Montplaisir J , Zadra A. Precipitating factors of somnambulism: impact of sleep deprivation and forced arousals. Neurology 2008; 70; 2274–5.
Plante DT , Winkelman J. Parasomnias. Psychiatr Clin North Am 2006; 29: 969–87.
Posthuma RB , Gagnon JF , Vendette M , et al. Quantifying the risk of neurodegenerative disease in idiopathic REM sleep behavior disorder. Neurology 2009; 72: 1296–300.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Percheron G. Les artères du thalamus humain: les artères choroïdiennes. Rev Neurol (Paris) 1977; 133: 547–58.
Segarra JM. Cerebral vascular disease and behavior. I. The syndrome of the mesencephalic artery (basilar artery bifurcation). Arch Neurol 1970; 22: 408–18.

Reference Title: Review

Reference Type: further-reading

Hermann DM , Siccoli M , Brugger P , et al. Evolution of neurological, neuropsychological and sleep-wake disturbances after paramedian thalamic stroke. Stroke 2008; 39: 62–8.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Bjornstad B , Goodman SH , Sirven JI , Dodick DW. Paroxysmal sleep as a presenting symptom of bilateral paramedian thalamic infarctions. Mayo Clin Proc 2003; 78: 347–9.
Culebras A. Neuroanatomic and neurologic correlates of sleep disturbances. Neurology 1992; 42 (Suppl. 6): S19–S27.
Matheus MG , Castillo M. Imaging of acute bilateral paramedian thalamic and mesencephalic infarcts. Am J Neuroradiol 2003; 24: 2005–8.
Rangel-Castilla L , Gasco J , Thompson B , Salinas P. Bilateral paramedian thalamic and mesencephalic infarcts after basilar tip aneurysm coiling: role of the artery of Percheron. Neurochirurgia (Astur) 2009; 20: 288–93.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Aguglia U , Gambardella A , Quattrone A. Sleep-induced masticatory myoclonus: a rare parasomnia associated with insomnia. Sleep 1991; 14: 80–2.

Reference Title: Review

Reference Type: further-reading

Loi D , Provini F , Vetrugno R , et al. Sleep-related faciomandibular myoclonus: a sleep-related movement disorder different from bruxism. Mov Disord 2007; 22: 1819–22.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Lavigne GJ , Manzini C , Kato T. Sleep bruxism. In: Kryger M , Roth T , Dement W , eds. Principles and Practice of Sleep Medicine, 4th edn. Philadelphia: WB Saunders Co., 2005; 946–59.
Vasiknanonte P , Kuasirikul S , Vasiknanonte S. Two faces of nocturnal tongue biting. J Med Assoc Thail 1997; 80: 500–7.
Vetrugno R , Provini F , Plazzi G , et al. Familial nocturnal facio-mandibular myoclonus mimicking sleep bruxism. Neurology 2002; 58: 644–7.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Review

Reference Type: further-reading

Dyken ME , Lin-Dyken DC , Yamada T. Diagnosing rhythmic movement disorder with video-polysomnography. Pediatr Neurol 1997; 16: 37–41.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
ASDA (American Sleep Disorders Association) . International Classification of Sleep Disorders, Revised: Diagnostic and Coding Manual. Rochester, Minnesota: American Sleep Disorders Association, 1997.
Etzioni T , Katz N , Hering E , et al. Controlled sleep restriction for rhythmic movement disorder. J Pediatr 2005; 3: 393–5.
Gharagozlou P , Seyffert M , Santos R , et al. Rhythmic movement disorder associated with respiratory arousals and improved by CPAP titration in a patient with restless legs syndrome and sleep apnea. Sleep Med 2009; 4: 501–3.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Reviews

Reference Type: further-reading

Koyano K , Tsukiyama Y , Ichiki R , Kuwata . Assessment of bruxism in the clinic. J Oral Rehabil 2008; 35: 495–508.
Lavigne GJ , Khoury S , Abe S , Yamaguchi T , Raphael K. Bruxism physiology and pathology: an overview for clinicians. J Oral Rehabil 2008; 35: 476–94.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Huynh N , Lavigne GJ , Lanfranchi PA , Montplaisir JY , de Champlain J. The effect of 2 sympatholytic medications – propranolol and clonidine – on sleep bruxism: experimental randomized controlled studies. Sleep 2006; 29: 307–16.
Lavigne GJ , Rompré PH , Montplaisir JY. Sleep bruxism: validity of clinical research diagnostic criteria in a controlled polysomnographic study. J Dent Res 1996; 75: 546–52.
Macedo CR , Silva AB , Machado MA , Saconato H , Prado GF. Occlusal splints for treating sleep bruxism (tooth grinding). Cochrane Database Syst Rev 2007; 17: CD005514.
Oksenberg A , Arons E. Sleep bruxism related to obstructive sleep apnea: the effect of continuous positive airway pressure. Sleep Med 2002; 3: 513–5.
Schwartz M , Freund B. Treatment of temporomandibular disorders with botulinum toxin. Clin J Pain 2002; 18 (6 Suppl.): S198–S203.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Reviews

Reference Type: further-reading

Karatas M. Restless legs syndrome and periodic limb movements during sleep: diagnosis and treatment. Neurologist 2007; 13: 294–301.
Walters AS , Lavigne G , Hening W , et al. The scoring of movements in sleep. J Clin Sleep Med 2007; 3: 155–67.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
AASM (American Academy of Sleep Medicine) . Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specification. Westchester, Illinois: American Academy of Sleep Medicine, 2007.
Chabli A , Michaud M , Montplaisir J. Periodic arm movements in patients with the restless legs syndrome. Eur Neurol 2000; 44: 133–8.
Hoban TF. Rhythmic movement disorder in children. CNS Spectr 2003; 8: 135–8.
Michaud M , Chabli A , Lavigne G , Montplaisir J. Arm restlessness in patients with restless legs syndrome. Mov Disord 2000; 15: 289–93.
Walters AS. Clinical identification of the simple sleep-related movement disorders. Chest 2007; 131: 1260–6.
Yokota T , Shiojiri T , Hirashima F. Sleep-related periodic arm movement. Sleep 1995; 18: 707–8.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Montagna P , Provini F , Plazzi G , Liguori R , Lugaresi E. Propriospinal myoclonus upon relaxation and drowsiness: a cause of severe insomnia. Mov Disord 1997; 12: 66–72.

Reference Title: Review

Reference Type: further-reading

Montagna P , Provini F , Vetrugno R. Propriospinal myoclonus at sleep onset. Neurophysiol Clin 2006; 36: 351–5.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Montagna P. Sleep-related non epileptic motor disorders. J Neurol 2004; 251: 781–94.
Vetrugno R , Provini F , Meletti S , et al. Propriospinal myoclonus at the sleep-wake transition: a new type of parasomnia. Sleep 2001; 24: 835–43.
Vetrugno R , Provini F , Plazzi G , Cortelli P , Montagna P. Propriospinal myoclonus: a motor phenomenon found in restless legs syndrome different from periodic limb movements during sleep. Mov Disord 2005; 10: 1323–9.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Oswald I. Sudden bodily jerks on falling asleep. Brain 1959; 82: 92–103.

Reference Title: Review

Reference Type: further-reading

Walters AS , Lavigne G , Hening W , et al. The scoring of movements in sleep. J Clin Sleep Med 2007; 3: 155–67.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Broughton R. Pathological fragmentary myoclonus, intensified sleep starts and hypnagogic foot tremor: three unusual sleep related disorders. In: Koella WP , Obal F , Schulz H , Wisser P , eds. Sleep 86, Proceedings of the Eighth European Congress on Sleep Research, Szeged Hungary, September 1986. New York: Fisher Verlag; 1988: 240–3.
Lins O , Castonguay M , Dunham W , Nevsimalova S , Broughton R. Excessive fragmentary myoclonus: time of night and sleep stage distributions. Can J Neurol Sci 1993; 20: 142–6.
Sander HW , Geisse H , Quinto C , Sachdeo R , Chokroverty S. Sensory sleep starts. J Neurol Neurosurg Psychiatry 1998; 64: 690.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Ekbom KA. Asthenia crurum paraesthetica (“Irritable Legs”). A new syndrome consisting of weakness, sensation of cold and nocturnal paraesthesia in the legs, responding to a certain extent to treatment in general. Acta Med Scand 1944; 118: 197–209.
Ekbom KA. Restless legs. JAMA 1946; 131: 481–6.
Ekbom KA. Growing pains and restless legs. Acta Paediatr Scand 1975; 64: 264–6.

Reference Title: Review

Reference Type: further-reading

Allen RP , Picchietti D , Hening WA , et al. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med 2003; 4: 101–19.

Reference Title: General

Reference Type: further-reading

American Psychiatric Association . Diagnostic and Statistical Manual of Mental Disorders, Text Revision (DSM IV-TR). Washington, DC: American Psychiatric Association, 2000.
Chervin RD , Ruzicka DL , Archbold KH , et al. Snoring predicts hyperactivity four years later. Sleep 2005; 28: 885–90.
Kotagal S , Silber MH. (2004). Childhood-onset restless legs syndrome. Ann Neurol 56: 803–7.
Ondo WG. Iron deficiency-associated restless legs syndrome. In: Ondo WG , ed. Restless Legs Syndrome: Diagnosis and Treatment. New York, NY: Informa Healthcare USA, 2008; 211–18.
Owens JA. The ADHD and sleep conundrum: a review. J Devel Behav Ped 2005; 26: 312–22.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Historical

Reference Type: further-reading

Schenck CH , Bundlie SR , Ettinger MG , Mahowald MW. Chronic behavioral disorders of human REM sleep: a new category of parasomnia. Sleep 1986; 9: 293–308.

Reference Title: Review

Reference Type: further-reading

Mahowald MW , Schenck CH. REM sleep behavior disorder. In Culebras A, ed. Sleep Disorders and Neurological Diseases, 2nd edn. New York: Informa Healthcare USA, 2007; 263–75.

Reference Title: General

Reference Type: further-reading

AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Culebras A. Sleep-disordered breathing in neuromuscular disease. Sleep Med Clin 2008; 3: 377–86.
Gordon PH , Cheng B , Katz IB , et al. The natural history of primary lateral sclerosis. Neurology 2006; 66: 647–53.
Younger DS , Chou S , Hays AP , et al. Primary lateral sclerosis. A clinical diagnosis reemerges. Arch Neurol 1988; 45: 1304–7.

Reference Title: Suggested reading

Reference Type: further-reading

Reference Title: Review

Reference Type: further-reading

Culebras A. Sleep-disordered breathing in neuromuscular disease. Sleep Med Clin 2008; 3: 377–86.

Reference Title: General

Reference Type: further-reading

Aboussouan LS , Lewis RA , Shy ME. Disorders of pulmonary function, sleep, and the upper airway in Charcot–Marie–Tooth disease. Lung 2007; 185: 1–7.
AASM (American Academy of Sleep Medicine) . International Classification of Sleep Disorders, 2nd edn.: Diagnostic and Coding Manual. Westchester, Illinois: American Academy of Sleep Medicine, 2005.
Culebras A. REM-sleep related diaphragmatic insufficiency. Neurology 1998; 50(Suppl. 4): 393–4.
Dematteis M , Pepin JL , Jeanmart M , et al. Charcot–Marie–Tooth disease and sleep apnoea syndrome: a family study. Lancet 2001; 357: 267–72.